Gaze recognition in high-functioning autistic patients: evidence from functional MRI   :   高機能自閉症患者における視線弁別に関する機能的MRI研究 

作成者 竹林, 啓子, 松本, 英夫, 小粥, 正博, 関根, 吉統, 鈴木, 勝昭, 松崎, 英夫, Suckling, John, 小澤, 福示郎, 福田, 倫明, 内山, 伊知郎, 中村, 和彦, 三辺, 義雄, 礒田, 治夫, 森, 則夫, 武井, 教使
作成者の別表記 Takebayashi, Hiroko, ヒロコ, タケバヤシ, Matsumoto, Hideo, ヒデオ, マツモト, Ogai, Masahiro, オガイ, マサヒロ, Sekine, Yoshimoto, ヨシモト, セキネ, Suzuki, Katsuaki, スズキ, カツアキ, Matsuzaki, Hideo, マツザキ, ヒデオ, Ozawa, Fukujirou, オザワ, フクジロウ, Fukuda, Rinmei, フクダ, リンメイ, Uchiyama, Ichiro, ウチヤマ, イチロウ, Nakamura, Kazuhiko, ナカムラ, カズヒコ, Minabe, Yoshio, ミナベ, ヨシオ, Isoda, Haruo, イソベ, ハルオ, Mori, Norio, モリ, ノリオ, Takei, Nori, タケイ, ノリ
キーワード等 high-functioning autism, gaze recognition; functional MRI, theory of mind
日本十進分類法 (NDC) 490
内容 We examined whether patients with high-functioning autistic disorder (AD) would exhibit abnormal activation in brain regions implicated in the functioning of theory of mind (TOM) during gaze recognition. We investigated brain activity during gaze recognition in 5 patients with high-functioning AD and 9 normal subjects, using functional magnetic resonance imaging. On the gaze task, more activation was found in the left middle frontal gyrus, the right intraparietal sulcus, and the precentral and inferior parietal gyri bilaterally in controls than in AD patients, whereas the patient group showed more powerful signal changes in the left superior temporal gyrus, the right insula, and the right medial frontal gyrus. These results suggest that high-functioning AD patients have functional abnormalities not only in TOM-related brain regions, but also in widely distributed brain regions that are not normally activated upon the processing of information from another person's gaze.
公開者 千葉医学会
コンテンツの種類 雑誌掲載論文 Journal Article
DCMI資源タイプ text
ファイル形式 application/pdf, text/html
ISSN 0303-5476
NCID AN00142148
掲載誌情報 千葉医学雑誌 Vol.82 no.3 page.139-147
情報源 Chiba medical journal
言語 英語
関連情報 (URL)
著者版フラグ publisher

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